liraglutide

Generic Name: liraglutide (LIR a GLOO tde)

Brand Names: Victoza

What is liraglutide?

Liraglutide is a diabetes medicine that helps control blood sugar levels.

Liraglutide is used to treat type 2 diabetes.

This medication is not for treating type 1 diabetes.

Liraglutide may also be used for purposes not listed in this medication guide.

What is the most important information I should know about liraglutide?

You should not use liraglutide if you are allergic to it, or if you have multiple endocrine neoplasia type 2 (tumors in your glands), a personal or family history of medullary thyroid cancer, insulin-dependent diabetes, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin)

Before using liraglutide, tell your doctor if you have stomach problems causing slow digestion, kidney or liver disease, high blood pressure, high triglycerides, or if you have ever had pancreatitis, gallstones, or alcoholism.

You should not breast-feed while using liraglutide. Never share an injection pen with another person. Sharing injection pens can allow disease such as hepatitis or HIV to pass from one person to another. Call your doctor at once if you have a serious side effect such as swelling or a lump in your throat area, hoarse voice, trouble swallowing, feeling short of breath, severe pain in your upper stomach spreading to your back, nausea and vomiting, or signs of infection such as fever, chills, sore throat, flu symptoms, mouth sores, or easy bruising or bleeding.

Liraglutide is only part of a complete program of treatment that may also include diet, exercise, weight control, foot care, eye care, dental care, and testing your blood sugar.

What should I discuss with my health care provider before using liraglutide?

You should not use liraglutide if you are allergic to it, or if you have:

• 
  

  multiple endocrine neoplasia type 2 (tumors in your glands);

  
  


• 
  

  a personal or family history of medullary thyroid cancer;

  
  


• 
  

  type 1 diabetes; or

  
  


• 
  

  if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

  
  

To make sure you can safely use liraglutide, tell your doctor if you have any of these other conditions:

• 
  

  stomach problems causing slow digestion;

  
  


• 
  

  kidney or liver disease;

  
  


• 
  

  a thyroid disorder;

  
  


• 
  

  high blood pressure;

  
  


• 
  

  high triglyceride levels in your blood;

  
  


• 
  

  a history of pancreatitis;

  
  


• 
  

  a history of gallstones; or

  
  


• 
  

  a history of alcoholism.

  
  

FDA pregnancy category C. It is not known whether liraglutide will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.. In animal studies, liraglutide caused the development of thyroid tumors. However, very high doses are used in animal studies. It is not known whether these effects would occur in people using doses recommended for human use. Ask your doctor about your personal risk. It is not known whether liraglutide passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using liraglutide.

How should I use liraglutide?

Liraglutide comes in a prefilled injection pen. Ask your pharmacist which type of needles are best to use with your pen.

Liraglutide is injected under the skin. Your care provider will show you the best places on your body to inject liraglutide. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and injection pens.

Liraglutide is usually given once per day. Your doctor may occasionally change your dose to make sure you get the best results. Your dose needs may change if you become ill, have a fever or infection, or if you have surgery or a medical emergency.

You may use liraglutide at any time of the day, with or without a meal.

Do not use liraglutide if it has changed colors or has particles in it. Call your doctor for a new prescription.

Your blood sugar will need to be checked often, and you may need other blood tests at your doctor's office. Visit your doctor regularly.

Low blood sugar (hypoglycemia) can occur if you skip a meal, exercise too long, drink alcohol, or are under stress. Symptoms include headache, hunger, confusion, irritability, drowsiness, weakness, dizziness, tremors, sweating, and fast heartbeat. Carry hard candy or glucose tablets with you in case you have low blood sugar. Other sugar sources include orange juice and milk. Be sure your family and close friends know how to help you in an emergency.

Liraglutide is only part of a complete program of treatment that may also include diet, exercise, weight control, foot care, eye care, dental care, and testing your blood sugar. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels.

Storing unopened injection pens: Store in the refrigerator. Do not store near the refrigerator's cooling element.

Storing after your first use: You may keep "in-use" injection pens in the refrigerator or at room temperature. Protect the pens from moisture, heat, and sunlight. Use within 30 days. Remove the needle before storing an injection pen, and keep the cap on the pen when not in use.

Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

Do not freeze liraglutide, and throw away the medication if it has become frozen.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose may cause severe nausea and vomiting.

What should I avoid while using liraglutide?

Never share an injection pen with another person. Sharing injection pens can allow disease such as hepatitis or HIV to pass from one person to another.

Liraglutide side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  swelling or a lump in your throat area;

  
  


• 
  

  hoarse voice, trouble swallowing, feeling short of breath;

  
  


• 
  

  pancreatitis - severe pain in your upper stomach spreading to your back, nausea and vomiting, loss of appetite, fast heart rate; or

  
  


• 
  

  signs of infection such as fever, chills, sore throat, flu symptoms, easy bruising or bleeding (nosebleeds, bleeding gums), mouth sores, unusual weakness.

  
  

Less serious side effects may include:

• 
  

  headache, dizziness;

  
  


• 
  

  upset stomach, loss of appetite;

  
  


• 
  

  nausea, vomiting;

  
  


• 
  

  diarrhea, constipation;

  
  


• 
  

  cold symptoms such as stuffy nose, sneezing, sinus pain, sore throat;

  
  


• 
  

  back pain;

  
  


• 
  

  tired feeling;

  
  


• 
  

  mild skin rash; or

  
  


• 
  

  redness or rash where the medicine was injected.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Liraglutide Dosing Information

Usual Adult Dose for Diabetes Mellitus Type II:

Initial dose: 0.65 mg subcutaneously once a day for at least 1 week. This dose is intended to reduce gastrointestinal symptoms during initial titration, and is not effective for glycemic control.
After one week, increase the dose to 1.2 mg. If the 1.2 mg dose does not result in acceptable glycemic control, the dose can be increased to 1.8 mg

What other drugs will affect liraglutide?

Liraglutide can make it harder for your body to absorb other medications you take by mouth. Tell your doctor about all medications you take by mouth, especially oral diabetes medications (Glucotrol, Metaglip, Amaryl, Avandaryl, Duetact, DiaBeta, Micronase, Glucovance, and others).

There may be other drugs that can interact with liraglutide. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More liraglutide resources

• Liraglutide Side Effects (in more detail)
• Liraglutide Dosage
• Liraglutide Use in Pregnancy & Breastfeeding
• Liraglutide Drug Interactions
• Liraglutide Support Group
• 142 Reviews for Liraglutide - Add your own review/rating

• liraglutide Subcutaneous Advanced Consumer (Micromedex) - Includes Dosage Information


• Liraglutide Professional Patient Advice (Wolters Kluwer)


• Liraglutide MedFacts Consumer Leaflet (Wolters Kluwer)


• Victoza Prescribing Information (FDA)


• Victoza Consumer Overview

Compare liraglutide with other medications

• Diabetes, Type 1
• Diabetes, Type 2
• Obesity

Where can I get more information?

• Your pharmacist can provide more information about liraglutide.

See also: liraglutide side effects (in more detail)

La Vaquita Extra Strength

Dosage Form: ointment
Drug Facts

Active Ingredient

• Methyl Salicylate 12%


• Menthol 3%


• Camphor 2%


• Eucalyptus Oil 1%
  

• Pain Reliever


• Pain Reliever


• Pain Reliever


• Pain Reliever

Uses

• Provides temporary relief from minor aches and pains associated with back-aches, arthritis, sore aching and strained muscles and joints.
  

Warnings

● External use only.  Avoid Contact with eyes mucous membranes and broken or irritated skin. Do not swallow. Do not use if allergic to salicylates.  Do not bandage. Do not apply external heat to the application area.

Keep away from reach of children

• Stop use and ask a doctor if:
  


• 
  
  • pain persists or irritation develops.
    
  
  

Directions

• Apply generously and gently massage affected area. Repeat 3 times daily. For children under 2 years of age consult a physician.
  

    

Inactive Ingredients

Petrolatum, Paraffin, Lanolin, D and C Red 17.

LA VAQUITA  EXTRA STRENGTH methyl salicylate  ointment

Product Information Product Type HUMAN OTC DRUG NDC Product Code (Source) 61734-090 Route of Administration TOPICAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength MENTHOL (MENTHOL) MENTHOL 3 g  in 100 g Methyl Salicylate (Methyl Salicylate) Methyl Salicylate 12 g  in 100 g CAMPHOR (SYNTHETIC) (CAMPHOR (SYNTHETIC)) CAMPHOR (SYNTHETIC) 2 g  in 100 g EUCALYPTUS OIL (EUCALYPTUS OIL) EUCALYPTUS OIL 1 g  in 100 g

Inactive Ingredients Ingredient Name Strength PETROLATUM 75 g  in 100 g PARAFFIN 7 g  in 100 g LANOLIN 0.001 g  in 100 g D&C RED NO. 17 0.0021 g  in 100 g

Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 61734-090-01 90 g In 1 CAN None 2 61734-090-02 100 g In 1 JAR None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
OTC monograph final	part348	11/07/2010

Labeler - Delon Laboratories (1990) Ltd (248364184)

Establishment
Name	Address	ID/FEI	Operations
Delon Laboratories (1990) Ltd		248364184	label, manufacture, pack

Revised: 11/2010Delon Laboratories (1990) Ltd

Lioresal Intrathecal

Generic Name: baclofen (Intrathecal route)

BAK-loe-fen

Intrathecal route(Solution)

Abrupt discontinuation of intrathecal baclofen, regardless of the cause, has resulted in sequelae that include high fever, altered mental status, exaggerated rebound spasticity, and muscle rigidity, that in rare cases has advanced to rhabdomyolysis, multiple organ-system failure and death. Careful attention to programming and monitoring of the infusion system, refill scheduling and procedures, and pump alarms is necessary to avoid abrupt discontinuation of the drug. Educate patients and caregivers about the early symptoms of baclofen withdrawal .

Commonly used brand name(s)

In the U.S.

• Gablofen


• Lioresal

Available Dosage Forms:

• Solution


• Kit

Therapeutic Class: Skeletal Muscle Relaxant, Centrally Acting

Chemical Class: Gamma Aminobutyric Acid (class)

Uses For Lioresal

Intrathecal baclofen is used to help relax certain muscles in your body. It relieves the spasms, cramping, and tightness of muscles caused by medical problems such as multiple sclerosis, cerebral palsy, or certain injuries to the spine. Intrathecal baclofen does not cure these problems, but it may allow other treatment, such as physical therapy, to be more helpful in improving your condition.

Intrathecal baclofen acts on the central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of the medicine's side effects.

This medicine is delivered by a drug pump directly into the spinal fluid of your back. A doctor will surgically place the pump and monitor the dose of the medication that is delivered by the pump. The dose of intrathecal baclofen will be different for different patients and will depend on the type of muscle tightness that you have.

Intrathecal baclofen is given only by or under the direct supervision of a doctor.

Before Using Lioresal

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

This medicine has been tested in children 4 years of age and older. Effective doses have not been shown to cause different side effects or problems in children than it does in adults. However, this medicine may not be safe for children younger than 4 years of age.

Geriatric

Side effects such as hallucinations, confusion or mental depression, other mood or mental changes, and severe drowsiness may be especially likely to occur in elderly patients, who may be more sensitive than younger adults to the effects of intrathecal baclofen.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Breathing difficulties or


• Stroke or other brain disease—Baclofen may make these conditions worse

• Communication difficulties or


• Spinal cord injuries, at or above T–6 or


• Withdrawal symptoms, history of—These conditions may increase your risk for side effects of baclofen

• Epilepsy or


• Kidney disease or


• Mental or emotional problems or


• Spinal lesions—The chance of side effects may be increased

• Parkinson's disease—Baclofen may make this condition worse

Proper Use of baclofen

This section provides information on the proper use of a number of products that contain baclofen. It may not be specific to Lioresal. Please read with care.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Precautions While Using Lioresal

Your doctor should check your progress at regular visits, especially during the first few weeks of treatment with this medicine. During this time, the amount of medicine you are using may have to be changed often to meet your individual needs.

Make sure to keep all appointments to refill the pump. If the pump is not refilled on time, you may experience return of your muscle tightness and early withdrawal symptoms which might include:

• itching of the skin


• decreased blood pressure
  
  • blurred vision
  
  
  • confusion
  
  
  • dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
  
  
  • sweating
  
  
  • unusual tiredness or weakness
  
  


• burning, crawling, itching, numbness, prickling, "pins and needles" , or tingling feelings


• seizures

Intrathecal baclofen will add to the effects of alcohol and other CNS depressants (medicines that may make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; other muscle relaxants; and anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using intrathecal baclofen.

Intrathecal baclofen may cause dizziness, drowsiness, false sense of well-being, lightheadedness, vision problems, or clumsiness or unsteadiness in some people. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert, well-coordinated, and able to see well.

Intrathecal baclofen may cause dryness of the mouth. For temporary relief, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if dry mouth continues for more than 2 weeks, check with your medical doctor or dentist. Continuing dryness of the mouth may increase the chance of dental disease, including tooth decay, gum disease, and fungus infections.

Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem.

Lioresal Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

• Convulsions (seizures)

Less common or rare

• Blurred vision or double vision


• fainting


• mental depression


• muscle weakness


• ringing or buzzing in ears


• seeing, hearing, or feeling things that are not there


• shortness of breath or troubled breathing

Symptoms of overdose

• Convulsions (seizures)


• dizziness, drowsiness, or lightheadedness


• increased watering of the mouth


• mental confusion


• muscle weakness


• nausea and/or vomiting


• shortness of breath or troubled breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Constipation


• difficult urination


• dizziness


• headache


• nausea and/or vomiting


• numbness or tingling in hands or feet


• sleepiness

Less common

• Clumsiness, unsteadiness, trembling, or other problems with muscle control


• diarrhea


• difficulty sleeping


• dizziness or lightheadedness, especially when getting up from a lying or sitting position


• dry mouth


• frequent urge to urinate


• irritation of the skin at the site where the pump is located


• itching of the skin


• sexual problems


• slurred speech or other speech problems


• swelling of ankles, feet, or lower legs


• trembling or shaking

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

• Convulsions (seizures)


• facial flushing, headache, increased sweating, or slow heartbeat


• increased muscle spasms


• seeing, hearing, or feeling things that are not there

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Lioresal Intrathecal side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Lioresal Intrathecal resources

• Lioresal Intrathecal Side Effects (in more detail)
• Lioresal Intrathecal Use in Pregnancy & Breastfeeding
• Drug Images
• Lioresal Intrathecal Drug Interactions
• Lioresal Intrathecal Support Group
• 5 Reviews for Lioresal Intrathecal - Add your own review/rating

• Lioresal Intrathecal Prescribing Information (FDA)


• Baclofen Prescribing Information (FDA)


• Baclofen Professional Patient Advice (Wolters Kluwer)


• Baclofen Monograph (AHFS DI)


• Baclofen MedFacts Consumer Leaflet (Wolters Kluwer)


• Gablofen Prescribing Information (FDA)


• Gablofen Consumer Overview


• Lioresal Prescribing Information (FDA)

Compare Lioresal Intrathecal with other medications

• Alcohol Withdrawal
• Cerebral Spasticity
• Cervical Dystonia
• Dystonia
• Hiccups
• Huntington's Disease
• Migraine Prevention
• Muscle Spasm
• Muscle Twitching
• Neuralgia
• Periodic Limb Movement Disorder
• Spasticity
• Trigeminal Neuralgia

Lo Loestrin Fe

Generic Name: norethindrone, ethinyl estradiol, and ferrous fumarate (Oral route)

ETH-i-nil es-tra-DYE-ol, nor-ETH-in-drone AS-e-tate, ETH-i-nil es-tra-DYE-ol, FER-us FUE-ma-rate

Oral route(Tablet)

Cigarette smoking increases the risk of serious cardiovascular events from combination oral contraceptives (COC) use. This risk increases with age, particularly in women over 35 years of age, and with the number of cigarettes smoked. For this reason, COCs should not be used by women who are over 35 years of age and smoke .

Commonly used brand name(s)

In the U.S.

• Lo Loestrin Fe

Available Dosage Forms:

• Tablet

Uses For Lo Loestrin Fe

Norethindrone, ethinyl estradiol, and ferrous fumarate combination is used to prevent pregnancy. It is a birth control pill that contains two types of hormones, ethinyl estradiol and norethindrone, and when taken properly, prevents pregnancy. It works by stopping a woman's egg from fully developing each month. The egg can no longer accept a sperm and fertilization is prevented.

This medicine also contains ferrous fumarate. Ferrous fumarate is an iron supplement.

No contraceptive method is 100 percent effective. Birth control methods such as having surgery to become sterile or not having sex are more effective than birth control pills. Discuss your options for birth control with your doctor.

This medicine does not prevent AIDS or other sexually transmitted diseases. It will not help as emergency contraception, such as after unprotected sexual contact.

This medicine is available only with your doctor's prescription.

Before Using Lo Loestrin Fe

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies on the relationship of age to the effects of norethindrone, ethinyl estradiol, and ferrous fumarate combination have not been performed in the pediatric population. However, pediatric-specific problems that would limit the usefulness of this medication in teenagers are not expected. This medicine may be used for birth control in teenage females but should not be used before the start of menstruation.

Geriatric

Appropriate studies on the relationship of age to the effects of norethindrone, ethinyl estradiol, and ferrous fumarate combination have not been performed in the geriatric population. This medicine should not be used in elderly women.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	X	Studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit.

Breast Feeding

Ethinyl Estradiol

Studies suggest that this medication may alter milk production or composition. If an alternative to this medication is not prescribed, you should monitor the infant for side effects and adequate milk intake.

Ethinyl EstradiolNorethindrone AcetateIron

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Boceprevir


• Eltrombopag


• Felbamate


• Isotretinoin


• Paclitaxel


• Paclitaxel Protein-Bound


• Theophylline


• Tizanidine


• Tranexamic Acid

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Alprazolam


• Amoxicillin


• Ampicillin


• Amprenavir


• Aprepitant


• Atazanavir


• Bacampicillin


• Betamethasone


• Bexarotene


• Bosentan


• Carbamazepine


• Cefdinir


• Colesevelam


• Cyclosporine


• Darunavir


• Delavirdine


• Demeclocycline


• Doxycycline


• Efavirenz


• Etravirine


• Fosamprenavir


• Fosaprepitant


• Fosphenytoin


• Gatifloxacin


• Ginseng


• Grepafloxacin


• Griseofulvin


• Lamotrigine


• Levodopa


• Levofloxacin


• Levothyroxine


• Licorice


• Lomefloxacin


• Methyldopa


• Minocycline


• Modafinil


• Moxifloxacin


• Mycophenolate Mofetil


• Mycophenolic Acid


• Nelfinavir


• Nevirapine


• Norfloxacin


• Ofloxacin


• Omeprazole


• Oxcarbazepine


• Oxytetracycline


• Penicillamine


• Phenobarbital


• Phenytoin


• Pioglitazone


• Prednisolone


• Primidone


• Rifabutin


• Rifampin


• Rifapentine


• Ritonavir


• Roflumilast


• Rosuvastatin


• Rufinamide


• Selegiline


• St John's Wort


• Telaprevir


• Temafloxacin


• Tetracycline


• Tipranavir


• Topiramate


• Troglitazone


• Troleandomycin


• Trovafloxacin Mesylate


• Valdecoxib


• Voriconazole


• Warfarin


• Zinc

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

• Caffeine


• Dairy Food


• Grapefruit Juice


• Phytic Acid Containing Food

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Abnormal or unusual vaginal bleeding or


• Blood clots, or history of or


• Breast cancer, active or history of or


• Diabetes with kidney, eye, nerve, or blood vessel damage or


• Heart attack, history of or


• Heart or blood vessel disease or


• Heart rhythm problems or


• Hypertension (high blood pressure), uncontrolled or


• Liver disease, including tumors or cancer or


• Migraine headache, new or worse or a new kind of headache or


• Problems with circulation or blood clots, now or in the past or


• Problems with heart valves or


• Stroke, history of—Should not be used in patients with these conditions.

• Angioedema (swelling of the face, tongue, or throat), inherited or


• Cervical cancer or intraepithelial neoplasia or


• Chloasma gravidarum (skin disorder during pregnancy), history of or


• Cholestasis (bile problem) during pregnancy, history of or


• Depression, history of or


• Diabetes or


• Dyslipidemia (high cholesterol or fats in the blood), uncontrolled or


• Gallbladder disease or


• Hypertension (high blood pressure), controlled—Use with caution. May make these conditions worse.

Proper Use of Lo Loestrin Fe

To make using hormonal contraceptives as safe and reliable as possible, you should understand how and when to use them and what effects may be expected.

This medicine comes with patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

This medicine is available in blister packs. Each blister pack contains 28 tablets with different colors that need to be taken in the same order as directed on the blister pack.

When you begin using this medicine, your body will require at least 7 days to adjust before a pregnancy will be prevented. Use a second form of contraception, such as a condom, spermicide, or diaphragm, for the first 7 days of your first cycle of pills.

Take this medicine at the same time each day. You may take this medicine with or without food.

Do not skip or delay taking your pill by more than 24 hours. If you miss a dose, you could get pregnant. Ask your doctor for ways to help you remember to take your pills or about using another method of birth control.

You may have light bleeding or spotting when you first take the pill.

You may feel sick or nauseous, especially during the first few months that you take this medicine. If your nausea is continuous and does not go away, call your doctor.

If you vomit or have diarrhea within 3 to 4 hours of taking this medicine, follow the instructions in the patient leaflet or call your doctor.

If you are switching from a combination hormonal method (e.g., another pill, patch, vaginal ring) to using Lo Loestrin Fe®, take the medicine on the day you would have taken your next pill. If you do not start your period, see your doctor for a pregnancy test. If you have used a vaginal ring or patch, finish the 21 days of use, and wait 7 days after the ring or patch is removed before you start taking this medicine. You must also use a second method of birth control (e.g., condom, diaphragm, spermicide) for the first 7 days you take this medicine.

If you are switching from a progestin-only method (e.g., progestin-only pill, implant, injection, intrauterine system) to using Lo Loestrin Fe®, take the medicine on the day you would have taken your next progestin-only pill, or on the day your implant is removed, or on the day you would have your next injection. If you switch from an IUD, talk to your doctor when to start taking this medicine. You must also use a second method of birth control (e.g., condom, diaphragm, spermicide) for the first 7 days you take this medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

Your doctor may ask you to begin your dose on the first day of your menstrual period (called Day 1 Start) or on the first Sunday after your menstrual period starts (called Sunday Start). When you begin on a certain day it is important that you follow that schedule, even if you miss a dose. Do not change your schedule on your own. If the schedule that you use is not convenient, check with your doctor about changing it. For a Sunday start, you need to use another form of birth control (e.g., condom, diaphragm, spermicide) for the first 7 days.

• For oral dosage form (tablets):
  
  • For contraception (to prevent pregnancy):
    
    • Adults and teenagers—One tablet taken at the same time each day for 28 days.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

Call your doctor or pharmacist for instructions.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using Lo Loestrin Fe

It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly and does not cause unwanted effects. These visits will usually be every 6 to 12 months, but some doctors require them more often.

Although you are using this medicine to prevent pregnancy, you should know that using this medicine while you are pregnant could harm the unborn baby. If you think you have become pregnant while using the medicine, tell your doctor right away.

Vaginal bleeding of various amounts may occur between your regular menstrual periods during the first 3 months of use. This is sometimes called spotting when slight, or breakthrough bleeding when heavier.

• If this should occur, continue with your regular dosing schedule.


• The bleeding usually stops within 1 week. Check with your doctor if the bleeding continues for more than 1 week.


• If bleeding continues after you have been taking hormonal contraceptives on schedule and for more than 3 months, check with your doctor.

Check with your doctor right away if you miss a menstrual period. Missed periods may occur if you skip one or more blue tablets and have not taken your pills exactly as directed. If you miss two periods in a row, talk to your doctor. You might need a pregnancy test.

If you suspect that you may be pregnant, stop using this medicine immediately and check with your doctor.

Do not use this medicine if you smoke cigarettes or if you are over 35 years old. If you smoke while using birth control pills, you increase your risk of having a heart attack, stroke, or blood clot. Your risk is even higher if you are over age 35, if you have diabetes, high blood pressure, high cholesterol, or if you are overweight. Talk with your doctor about ways to stop smoking. Keep your diabetes under control. Ask your doctor about diet and exercise to control your weight and blood cholesterol level.

Stop using this medicine and check with your doctor right away if you have pain in the chest, groin, or legs, especially the calves; difficulty with breathing; a sudden, severe headache; slurred speech; a sudden, unexplained shortness of breath; a sudden loss of coordination; or vision changes while using this medicine.

Check with your doctor immediately if you have trouble wearing contact lenses or if blurred vision, difficulty with reading, or any other change in vision occurs during or after treatment. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).

Stop using this medicine and check with your doctor right away if you have pain or tenderness in the upper stomach; pale stools; dark urine; loss of appetite; nausea; unusual tiredness or weakness; or yellow eyes or skin. These could be symptoms of a serious liver problem.

Check with your doctor before refilling an old prescription, especially after a pregnancy. You will need another physical examination and your doctor may change your prescription.

Make sure any doctor or dentist who treats you knows that you are using this medicine. You may need to stop using this medicine several days before having surgery or certain medical tests.

This medicine may cause skin discoloration. Use a sunscreen when you are outdoors. Avoid sunlamps and tanning beds.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal (e.g., St. John's wort) or vitamin supplements.

Lo Loestrin Fe Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

• Breast tenderness


• heavy non-menstrual vaginal bleeding


• irregular menstrual periods


• longer or heavier menstrual periods


• normal menstrual bleeding occurring earlier, possibly lasting longer than expected

Incidence not known

• Chest pain


• chills


• clay-colored stools


• confusion


• dark urine


• diarrhea


• difficulty with speaking


• dizziness


• double vision


• fast or irregular heartbeat


• fever


• headache


• inability to move the arms, legs, or facial muscles


• inability to speak


• indigestion


• itching


• loss of appetite


• nausea


• pain, redness, or swelling in the arm or leg


• pains in the chest, groin, or legs, especially in the calves of the legs


• rash


• severe headaches of sudden onset


• severe nausea or vomiting


• slurred speech


• stomach pain


• sudden loss of coordination


• sudden onset of shortness of breath for no apparent reason


• sudden onset of slurred speech


• sudden vision changes


• tightness in the chest


• unpleasant breath odor


• unusual tiredness or weakness


• unusual warmth or flushing of the skin


• unusually heavy or unexpected menstrual bleeding


• vaginal bleeding or spotting


• vomiting of blood


• yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

• Vomiting

Less common

• Anxiety


• blemishes on the skin


• cramps


• depression


• heavy bleeding


• pain


• pimples


• weight changes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Lo Loestrin Fe side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Lo Loestrin Fe resources

• Lo Loestrin Fe Side Effects (in more detail)
• Lo Loestrin Fe Use in Pregnancy & Breastfeeding
• Lo Loestrin Fe Drug Interactions
• 58 Reviews for Lo Loestrin Fe - Add your own review/rating

• Lo Loestrin Fe MedFacts Consumer Leaflet (Wolters Kluwer)


• Lo Loestrin Fe Prescribing Information (FDA)


• Lo Loestrin Fe Consumer Overview


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• Femhrt Prescribing Information (FDA)


• Femhrt Consumer Overview


• Femhrt MedFacts Consumer Leaflet (Wolters Kluwer)


• Jevantique Prescribing Information (FDA)


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• Loestrin 24 Fe Consumer Overview


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• Birth Control

Lithostat

Pronunciation: ass-EE-toe-high-drox-AM-ic
Generic Name: Acetohydroxamic Acid
Brand Name: Lithostat

Lithostat is used for:

Treating certain types of chronic urinary infections (urea-splitting) in combination with surgery (for patients with stones) or antibiotic medicines. It may also be used for other conditions as determined by your doctor.

Lithostat is a urease inhibitor. It works by decreasing ammonia levels and pH in the urine. This helps antibiotics to work better and decreases kidney stone formation.

Do NOT use Lithostat if:

• you are allergic to any ingredient in Lithostat


• you have a urinary infection that can be controlled by other medications or surgery


• your urine is infected by bacteria that do not respond to Lithostat


• you have severe kidney problems


• you are pregnant, or you are able to become pregnant and are not using an appropriate form of birth control

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lithostat:

Some medical conditions may interact with Lithostat. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have liver or kidney problems, bone marrow problems, blood vessel problems, or a history of blood clots

Some MEDICINES MAY INTERACT with Lithostat. However, no specific interactions with Lithostat are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Lithostat may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lithostat:

Use Lithostat as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Lithostat on an empty stomach at least 1 hour before or 2 hours after eating.


• Lithostat comes with an additional patient leaflet. Read it carefully and reread it each time you get Lithostat refilled.


• Do not take iron supplements or vitamins containing iron while you are using Lithostat, unless otherwise directed by your doctor.


• Continue to use Lithostat even if you feel well. Do not miss any doses.


• If you miss a dose of Lithostat, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Lithostat.

Important safety information:

• Talk with your doctor before using alcohol while taking Lithostat. You may develop a rash and general sensation of warmth if you consume alcoholic beverages while taking Lithostat.


• Women must use an effective form of birth control while taking Lithostat.


• LAB TESTS, including liver function, kidney function, and blood counts, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.


• Caution is advised when using Lithostat in CHILDREN because they may be more sensitive to its effects.


• PREGNANCY and BREAST-FEEDING: Do not use Lithostat if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. If you are able to become pregnant, talk with your doctor or pharmacist about the use of effective birth control while using Lithostat. It is unknown if Lithostat is excreted in breast milk. Do not breast-feed while taking Lithostat.

Possible side effects of Lithostat:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Anxiety; general body discomfort; hair loss; loss of appetite; mild headaches; nausea; nervousness; shakiness; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood vessel inflammation; calf pain, swelling, or tenderness; dark urine; depression; emotional or mood changes; irregular heartbeat; severe nausea, vomiting, or fatigue; unusual tiredness or weakness; yellowing of skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Lithostat side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include anxiety; diminished sense of well-being; severe anxiety, nausea, or vomiting; sluggishness.

Proper storage of Lithostat:

Store Lithostat at room temperature, between 59 and 86 degrees F (15 and 30 degrees C) in a tightly sealed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lithostat out of the reach of children and away from pets.

General information:

• If you have any questions about Lithostat, please talk with your doctor, pharmacist, or other health care provider.


• Lithostat is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Lithostat. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Lithostat resources

• Lithostat Side Effects (in more detail)
• Lithostat Use in Pregnancy & Breastfeeding
• Lithostat Drug Interactions
• Lithostat Support Group
• 1 Review for Lithostat - Add your own review/rating

• Lithostat Concise Consumer Information (Cerner Multum)

Compare Lithostat with other medications

• Bladder Infection
• Urinary Tract Infection

Latanoprost Drops

Pronunciation: la-TAN-oh-prost
Generic Name: Latanoprost
Brand Name: Xalatan

Latanoprost Drops are used for:

Treating increased pressure in the eye (ocular hypertension) and open-angle glaucoma.

Latanoprost Drops are a prostaglandin analog. It works to lower pressure in the eye by increasing fluid drainage from the eye.

Do NOT use Latanoprost Drops if:

• you are allergic to any ingredient in Latanoprost Drops


• you have inflammation in the eye (eg, iritis, uveitis)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Latanoprost Drops:

Some medical conditions may interact with Latanoprost Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have swelling, infection, or injury of the eye, or you have a history of inflammation in the eye (eg, iritis, uveitis)


• if you do not have a lens in your eye or have had the lens in your eye replaced


• if you have other types of glaucoma (eg, narrow-angle, neovascular)


• if you will be having eye surgery

Some MEDICINES MAY INTERACT with Latanoprost Drops. However, no specific interactions with Latanoprost Drops are known at this time.

Ask your health care provider if Latanoprost Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Latanoprost Drops:

Use Latanoprost Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Use Latanoprost Drops in the evening unless your doctor tells you otherwise.


• Soft contact lenses may absorb a chemical in Latanoprost Drops. Remove contact lenses before you use Latanoprost Drops; lenses may be placed back in the eyes 15 minutes after use of Latanoprost Drops.


• Wash your hands before and after using Latanoprost Drops.


• Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.


• To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.


• Use Latanoprost Drops at least 5 minutes apart from any other medicine that you put in your eye, especially eye drops that contain thimerosal.


• Continue to use Latanoprost Drops even if you feel well. Do not miss any doses.


• If you miss a dose of Latanoprost Drops, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Latanoprost Drops.

Important safety information:

• Latanoprost Drops are for use in the eye only. Do not get it in your nose or mouth.


• Latanoprost Drops may cause blurred vision or make your eyes more sensitive to light. Use Latanoprost Drops with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it. If your eyes become sensitive to light, wearing sunglasses may help.


• Latanoprost Drops may cause the colored part of your eye (iris) to turn brown. This change may be permanent. It may not be noticeable for several months to years. If it occurs, you will need to have regular eye examinations. Discuss any questions or concerns with your doctor.


• Latanoprost Drops may cause your eyelids to darken. It may also cause changes in the way that your eyelashes grow (eg, length, thickness, number of lashes). These effects usually go away after you stop using Latanoprost Drops. Discuss any questions or concerns with your doctor.


• Do NOT use more than the recommended dose without checking with your doctor.


• If you will be having eye surgery, tell your doctor that you use Latanoprost Drops.


• Lab tests, including eye pressure, may be performed while you use Latanoprost Drops. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Latanoprost Drops should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Latanoprost Drops while you are pregnant. It is not known if Latanoprost Drops are found in breast milk. If you are or will be breast-feeding while you use Latanoprost Drops, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Latanoprost Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; changes in eyelash growth; cold symptoms; eye burning, dryness, itching, or stinging; feeling of having something in your eye; increased tear production.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; darkening of the eyelid or eye color; eye or eyelid discharge, inflammation, irritation, pain, redness, or swelling; red, swollen, blistered, or peeling skin; vision changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Latanoprost side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Latanoprost Drops:

Store unopened bottles in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Do not freeze. Opened bottles may be stored at room temperature, up to 77 degrees F (25 degrees C), for up to 6 weeks. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Latanoprost Drops out of the reach of children and away from pets.

General information:

• If you have any questions about Latanoprost Drops, please talk with your doctor, pharmacist, or other health care provider.


• Latanoprost Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• Do not use Latanoprost Drops for other health conditions.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Latanoprost Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Latanoprost resources

• Latanoprost Side Effects (in more detail)
• Latanoprost Use in Pregnancy & Breastfeeding
• Latanoprost Drug Interactions
• Latanoprost Support Group
• 5 Reviews for Latanoprost - Add your own review/rating

Compare Latanoprost with other medications

• Glaucoma, Open Angle
• Intraocular Hypertension

Lescol

Pronunciation: FLOO-va-STAT-in
Generic Name: Fluvastatin
Brand Name: Lescol

Lescol is used for:

Lowering high cholesterol and triglycerides in certain patients. It also increases high-density lipoprotein (HDL, "good") cholesterol levels. It is used along with an appropriate diet. It is used in certain patients to slow blood vessel blockage and to reduce the need for medical procedures to open blocked heart blood vessels. It may also be used for other conditions as determined by your doctor.

Lescol is an HMG-CoA reductase inhibitor, also known as a "statin." It works by reducing the production of certain fatty substances in the body, including cholesterol.

Do NOT use Lescol if:

• you are allergic to any ingredient in Lescol


• you have liver problems or unexplained abnormal liver function tests


• you are pregnant or breast-feeding

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lescol:

Some medical conditions may interact with Lescol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have low blood pressure, a serious infection, kidney problems, diabetes, or a history of seizures


• if you have metabolism, hormonal, or electrolyte problems


• if you drink alcohol or have a history of liver problems or alcohol abuse


• if you have recently had major surgery or a serious injury


• if you have a certain type of high cholesterol (homozygous familial hypercholesterolemia)

Some MEDICINES MAY INTERACT with Lescol. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Azole antifungals (eg, fluconazole), colchicine, erythromycin, fibrates (eg, clofibrate, gemfibrozil), H₂ blockers (eg, ranitidine), immunosuppressants (eg, cyclosporine), niacin, or omeprazole because they may increase the risk of muscle or kidney problems


• Anticoagulants (eg, warfarin) because the risk of bleeding may be increased


• Rifampin because it may decrease Lescol's effectiveness


• Cimetidine, digoxin, glyburide, ketoconazole, phenytoin, or spironolactone because the risk of their side effects may be increased by Lescol

This may not be a complete list of all interactions that may occur. Ask your health care provider if Lescol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lescol:

Use Lescol as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Lescol by mouth with or without food.


• If you take cholestyramine or colestipol, ask your doctor or pharmacist how to take it with Lescol.


• Continue to take Lescol even if you feel well. Do not miss any doses.


• If you miss a dose of Lescol, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Lescol.

Important safety information:

• Lescol may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Lescol with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Drinking alcohol daily or in large amounts may increase the risk of liver problems with Lescol. Check with your doctor before drinking alcohol while you are taking Lescol.


• Follow the diet and exercise program given to you by your health care provider.


• Tell your doctor or dentist that you take Lescol before you receive any medical or dental care, emergency care, or surgery.


• Women who may become pregnant should use effective birth control while taking Lescol. Check with your doctor if you have questions about using birth control.


• Do NOT take more than the recommended dose without checking with your doctor.


• Report any unexplained muscle pain, tenderness, or weakness to your doctor right away, especially if you also have a fever or general body discomfort.


• Lab tests, including blood cholesterol levels and liver function tests, may be performed while you use Lescol. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Lescol should be used with extreme caution in CHILDREN younger than 9 years old and in those who have been having a menstrual period for less than one year; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Do not use Lescol if you are pregnant. It may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. Lescol is found in breast milk. Do not breast-feed while you are taking Lescol.

Possible side effects of Lescol:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Headache; stomach pain or upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); change in the amount of urine produced; chest pain; dark urine; fever, chills, or persistent sore throat; flu-like symptoms; joint pain; mental or mood changes; muscle pain, tenderness, or weakness (with or without fever or fatigue); numbness or tingling of the skin, arm, or leg; painful or frequent urination; pale stools; red, swollen, blistered, or peeling skin; severe stomach pain; yellowing of the eyes or skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Lescol side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Lescol:

Store Lescol at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Keep Lescol out of the reach of children and away from pets.

General information:

• If you have any questions about Lescol, please talk with your doctor, pharmacist, or other health care provider.


• Lescol is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Lescol. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Lescol resources

• Lescol Side Effects (in more detail)
• Lescol Dosage
• Lescol Use in Pregnancy & Breastfeeding
• Drug Images
• Lescol Drug Interactions
• Lescol Support Group
• 2 Reviews for Lescol - Add your own review/rating

• Lescol Prescribing Information (FDA)


• Lescol Consumer Overview


• Lescol Monograph (AHFS DI)


• Lescol Advanced Consumer (Micromedex) - Includes Dosage Information


• Fluvastatin Professional Patient Advice (Wolters Kluwer)

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• High Cholesterol
• High Cholesterol, Familial Heterozygous
• Hyperlipoproteinemia
• Hyperlipoproteinemia Type IIa, Elevated LDL
• Hyperlipoproteinemia Type IIb, Elevated LDL VLDL

Liqui-Minic Infant

Generic Name: pheniramine/pyrilamine/phenylpropanolamine (fen IR a meen/pie RILL a meen/fen ill proe pa NOLE a meen)

Brand Names: Liqui-Minic Infant, Triactin, Triaminic Infant, Triaminic Pediatric

What is Liqui-Minic Infant (pheniramine/pyrilamine/phenylpropanolamine)?

Pheniramine and pyrilamine are antihistamines. They block the effects of the naturally occurring chemical histamine in the body. Pheniramine and pyrilamine prevent sneezing; itchy, watery eyes and nose; and other symptoms of allergies and hay fever.

Phenylpropanolamine is a decongestant. It constricts (shrinks) blood vessels (veins and arteries). This reduces the blood flow to certain areas and allows nasal and respiratory (breathing) passages to open up.

Pheniramine/pyrilamine/phenylpropanolamine is used to treat nasal congestion and sinusitis (inflammation of the sinuses) associated with allergies, hay fever, and the common cold.

Phenylpropanolamine, an ingredient in this product, has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.

Pheniramine/pyrilamine/phenylpropanolamine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Liqui-Minic Infant (pheniramine/pyrilamine/phenylpropanolamine)?

Phenylpropanolamine, an ingredient in this product, has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.

Pheniramine/pyrilamine/phenylpropanolamine may cause dizziness or drowsiness. Avoid climbing and other hazardous activities while taking this medication. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking pheniramine/pyrilamine/phenylpropanolamine.

Do not take more of this medication than is recommended. If your symptoms do not improve, or if they worsen, talk to your doctor.

Who should not take Liqui-Minic Infant (pheniramine/pyrilamine/phenylpropanolamine)?

Do not take pheniramine/pyrilamine/phenylpropanolamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Before taking this medication, tell your doctor if you have

• kidney disease,


• liver disease,


• 
  

  diabetes,

  
  


• 
  

  glaucoma,

  
  


• 
  

  any type of heart disease or high blood pressure,

  
  


• 
  

  thyroid disease,

  
  


• 
  

  emphysema or chronic bronchitis, or

  
  


• 
  

  difficulty urinating or have an enlarged prostate.

  
  

You may not be able to take pheniramine/pyrilamine/phenylpropanolamine, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Pheniramine/pyrilamine/phenylpropanolamine is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant. This medication passes into breast milk and may harm a nursing baby. Do not take this medication without first talking to your doctor if you are breast-feeding a baby. If you are over 65 years of age, you may be more likely to experience side effects from pheniramine/pyrilamine/phenylpropanolamine. You may require a lower dose of this medication. Read the package label for directions or consult your doctor or pharmacist before treating a child with this medication. Children are more susceptible than adults to the effects of medicines and may have unusual reactions.

How should I take Liqui-Minic Infant (pheniramine/pyrilamine/phenylpropanolamine)?

Take pheniramine/pyrilamine/phenylpropanolamine exactly as directed. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

Take each dose with a full glass of water. Do not crush, chew, or break the long-acting or sustained-release forms of this medication. Swallow them whole. If you are unsure of the formulation of the medicine, ask your pharmacist for help. If you cannot swallow the tablets or capsules, look for a liquid form of the medication.

To ensure that you get a correct dose, measure the liquid forms of pheniramine/pyrilamine/phenylpropanolamine with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Do not take more of this medication than is recommended. An overdose of this medication can cause serious harm.

Do not take pheniramine/pyrilamine/phenylpropanolamine for longer than 7 days in a row. If your symptoms do not improve, if they get worse, or if you have a fever, talk to your doctor.

Store pheniramine/pyrilamine/phenylpropanolamine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a pheniramine/pyrilamine/phenylpropanolamine overdose include a dry mouth, large pupils, flushing, nausea, and vomiting.

What should I avoid while taking pheniramine/pyrilamine/ phenylpropanolamine?

Pheniramine/pyrilamine/phenylpropanolamine may cause dizziness or drowsiness. Avoid climbing and other hazardous activities while taking this medication. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while taking pheniramine/pyrilamine/phenylpropanolamine.

Pheniramine/pyrilamine/phenylpropanolamine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if pheniramine/pyrilamine/phenylpropanolamine is taken with any of these medications.

Pheniramine/ pyrilamine/phenylpropanolamine side effects

Serious side effects are unlikely to occur. Stop taking pheniramine/pyrilamine/ phenylpropanolamine and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take pheniramine/pyrilamine/phenylpropanolamine and talk to your doctor or try another similar medication if you experience

• 
  

  dryness of the eyes, nose, and mouth;

  
  


• 
  

  drowsiness or dizziness;

  
  


• 
  

  blurred vision;

  
  


• 
  

  difficulty urinating; or

  
  


• 
  

  excitation in children.

  
  

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect pheniramine/ pyrilamine/phenylpropanolamine?

Do not take pheniramine/pyrilamine/phenylpropanolamine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Do not take other over-the-counter cough, cold, allergy, diet, or sleep aids while taking pheniramine/pyrilamine/phenylpropanolamine without first talking to your doctor or pharmacist. Other medications may also contain pheniramine, pyrilamine phenylpropanolamine, or other similar drugs. You may accidentally take too much of these medicines.

Pheniramine/pyrilamine/phenylpropanolamine may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, other antihistamines, pain relievers, anxiety medicines, seizure medicines, and muscle relaxants. Dangerous sedation, dizziness, or drowsiness may occur if pheniramine/pyrilamine/phenylpropanolamine is taken with any of these medications.

Drugs other than those listed here may also interact with pheniramine/pyrilamine/phenylpropanolamine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

More Liqui-Minic Infant resources

• Liqui-Minic Infant Drug Interactions
• Liqui-Minic Infant Support Group
• 0 Reviews for Liqui-Minic Infant - Add your own review/rating

• Triactin MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Liqui-Minic Infant with other medications

• Allergies
• Eye Redness/Itching
• Hay Fever
• Nasal Congestion
• Pruritus
• Sinusitis
• Upper Respiratory Tract Infection

Where can I get more information?

• Your pharmacist has additional information about pheniramine/pyrilamine/phenylpropanolamine written for health professionals that you may read.

What does my medication look like?

Pheniramine/pyrilamine/phenylpropanolamine is available over the counter under the brand name Triaminic Oral Infant Drops. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.